Chronic voluntary alcohol consumption results in tolerance to sedative/hypnotic and hypothermic effects of alcohol in hybrid mice

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Effect of Adaptation to Alcohol and of Age on Voluntary Consumption of Alcohol by Rats.

If an ethanol solution of more than about 6 % concentration is the only fluid available to rats, their intake is at first low compared with that of water (Richter, 1953). But the amounts taken daily increase steadily up to a certain level. Thus it might be expected that rats that have first a period of free choice between alcohol and water and subsequently receive alcohol solution alone for som...

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Voluntary and forced exercises prevent the development of tolerance to analgesic effects of morphine in rats

Objective(s):Morphine is widely used to treat chronic pain. However, its utility is hindered by the development of tolerance to its analgesic effects. Despite the renowned beneficial effects of physical exercise on cognitive functions and signs of morphine withdrawal in morphine-dependent rats, little is known about the roles of voluntary and forced exercises in tolerance to analgesic effect of...

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ژورنال

عنوان ژورنال: Pharmacology Biochemistry and Behavior

سال: 2013

ISSN: 0091-3057

DOI: 10.1016/j.pbb.2012.12.025